Born in Armenia, Narine Yeghiyan graduated from the State Conservatory in Yerevan, where she studied from 2001 to 2006 majoring in opera singing with Professor Nelly Pirumova. Later Yeghiyan had further training with a two year postgraduate degree, which she completed in 2008.
On the stage of the Conservatory, Yeghiyan sang the role of Serpina in "La serva padrona", Fanni in "La di matrimonio cambiale", Georgette in "Suor Angelica". Yeghiyan in 2006 and 2008 won the first and third prize at singing competitions in Yerevan.
From 2009 to 2011 Yeghiyan was a guest soloist at the National Opera and Ballet Theatre in Yerevan where she sang the role of Donna Anna in Mozart's "Don Giovanni" and Inez in Verdi's "Il Trovatore".
Yeghiyan has participated in numerous master classes with Brigitte part Fassbaender, Deborah Polaski, Francisco Araiza and Grace Bumbry. In 2009, Yeghiyan got through to the semi final and was awarded a special price of Liz Mohn Culture and Music Foundation at the International Singing Competition "New Voices" in Germany. In 2010 and 2011 Yeghiyan participated in the singing contest "Competizione dell'Opera", Plácido Domingo's "Operalia".
In 2013 Narine Yeghiyan was a fellow of the Richard Wagner Society. From 2011-2013 Yeghiyan was a Fellow of Liz Mohn Culture and Music Foundation and a member of the Opera Studio of the Staatsoper Unter den Linden. On the State Opera stage, she sang Barbarina in "Le nozze di Figaro" under the direction of Daniel Barenboim, as Angelo Custode and heavenly voice in "Rappresentatione di Anima et di Corpo" under the direction of René Jacobs, as Tybalt in "Don Carlo", as Cinderella in "Cinderella" and others.
Yeghiyan's repertoire includes, among other things, the role of Pamina in "The Magic Flute", Annie in "Der Freischütz", Adina in "L'elisir d'amore", Mimì in "La Bohème," Magda in "La Rondine" and Nedda in "Il Pagliacci".
Since the 2013/14 season, Narine Yeghiyan is a member of the Ensemble of Berlin State Opera.